Oral complications of chemotherapy and head/neck radiation

Oral complications of chemotherapy and head/neck radiation

Also known as: Chemotherapy, oral complications; Head/neck radiation therapy, oral complications

The oral cavity is at high risk of side effects from chemotherapy and radiation therapy for a number of reasons.

Chemotherapy and radiation therapy stop the growth of rapidly dividing cells, such as cancer cells. Since normal cells in the lining of the mouth also divide rapidly, anticancer treatment can prevent cells in the mouth from reproducing, making it difficult for oral tissue to repair itself.

The mouth contains hundreds of different bacteria, some helpful and some harmful. Chemotherapy and radiation therapy can cause changes in the lining of the mouth and production of saliva and can upset the healthy balance of bacteria. These changes may lead to mouth sores, infections and tooth decay.

Wear and tear occur from normal use of the mouth, teeth and jaws, making healing more difficult.

Providence Oral, Head and Neck Cancer Program offers world-class care for patients with benign and malignant tumors of the oral cavity (mouth), tongue, pharynx (throat), larynx (voice box), nose, paranasal sinuses, salivary glands and thyroid gland, as well as tumors at the skull base.

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From the experts

Ask an Expert: Chemotherapy and insomnia

Q: I'm undergoing chemo, and though I am experiencing heavy-duty fatigue, I am also suffering from insomnia! Sometimes it's hard to fall asleep; other nights I wake up around 3 a.m. for an hour or two. My medical oncologist said chemo can disrupt the sleep-wake cycle and prescribed Ambien. I don't like the idea of relying on a sleeping pill. Anything else I can do?

Answer from Miles Hassell, M.D., director of Providence Integrative Medicine at Providence Cancer Center:

What to include in a chemo-recovery kit

Is someone you care about going through chemotherapy? Sometimes it’s hard to know how to help. Here’s one idea: Get together with others in your loved one’s family or circle and put together a chemo-recovery kit.

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